With over 2 million media fill simulations to date, across a range of complex presentations with zero failure rate, Nova Laboratories offer an unparalleled level of microbial quality assurance.

Sterile Manufacturing

Aseptically Manufactured Products

Nova Laboratories has a worldwide reputation for capability in novel, complex aseptic processing of pharmaceutical, biopharmaceutical and medical device products, at scales to support pre-clinical testing through to large Phase III trials. Our unique ability to design, construct and develop our own cleanrooms, isolators and associated process equipment allows us to offer a range of innovative and bespoke solutions, to meet your specific outsourcing requirements.

We have extensive experience in filling a wide range of products, either formulated in-house or pre-formulated, including:

  • Small Molecules
  • Peptides
  • Proteins
  • Monoclonal and Polyclonal Antibodies
  • Immunoconjugates
  • DNA Plasmids
  • Live Biologicals (category 1 and 2 bacteria, viruses and phages)

Licenced Products

  • Nova Laboratories Ltd has developed Xaluprine, in the treatment of acute lymphoblastic leukemia. Our dedicated Xaluprine website can be found using at www.xaluprine.com
  • Xaluprine is available in most European countries
  • Xaluprine offers patients’ parents of children and healthcare professionals a liquid formulation alternative to Mercaptopurine tablets
  • For children, Xaluprine is a significant improvement over the existing tablet presentation and gives benefits including more accurate dosing; flexibility of dosing; consistency in dosing and improved palatability
  • Following the success of Xaluprine, Nova is in the process of developing other lines of licenced products

Large Scale Commercial Manufacturing

Nova has several long established relationships with international pharmaceutical companies, providing large scale sterile and non-sterile manufacturing facilities.

Nova is now a specialist in this area and would be very interested to explore long terms joint venture or partnership arrangements with new clients.

Capability

Nova Laboratories’ gassed isolator technology has been used for aseptic manufacture of liquids, semi-solids and powders, in a wide range of pharmaceutical presentations, including:

  • Injection Vials (1ml - 200ml)
  • Ampoules (1ml - 30ml)
  • Prefilled Syringes (0.5ml - 50ml)
  • Pouches
  • Infusion Bags
  • Novel Injector Devices (assembly and filling)
  • Inhaled Products
  • Opthalmic Products


We also have extensive experience in the aseptic manufacture and filling of the following product types:

  • Injectable water-in-oil emulsions
  • Injectable oil-in-water emulsions
  • Injectable suspensions
  • Injectable nano-dispersions
  • Injectable liposomes
  • Lyophilized products
  • Spray dried products

Capacity

We can offer filling of pharmaceutical and biopharmaceutical products for clinical trials in a number of isolator configurations, using both manual and automated filling techniques.

  • 4 glove Isolator (up to 800 x 10ml vials and 1200 x 2ml vials)
  • 8 glove Isolator (up to 2400 x 10ml vials and 4000 x 2ml vials)
  • 14 glove Isolator (up to 10,000 x 2ml vials )
  • 14 glove filling isolator + 8 glove transfer isolator (up to 10,000 x 10ml vials)

Speciality

Nova specialises in filling low volume liquids and powders:

  • Liquids from 0.1g +/- 0.002g
  • Powders from 0.5g +/- 0.05g
  • Nanogram quantities of gold particles

Our Laboratory Facility

Watch our video and take a tour of our state-of-the-art laboratory facility.

Our Other Services

Nova Laboratories offer expertise in the following three other service areas:

Contact Us

For all product enquires, please contact our customer services team on 0800 975 48 40 or alternatively, you can email us at [email protected]